• SJ AWAN Lahore Medical Research centre, Lahore, Pakistan
  • Z FATIMA Department of Zoology, Kinnaird College For Women, Lahore, Pakistan
  • S KAMRAN Department of Zoology, Kinnaird College For Women, Lahore, Pakistan
  • AS KHAN Department of Zoology, Kinnaird College For Women, Lahore, Pakistan
  • T FATIMA Department of Zoology, Kinnaird College For Women, Lahore, Pakistan
  • S IMRAN Department of Zoology, Kinnaird College For Women, Lahore, Pakistan
  • M SHABBIR Department of Zoology, Kinnaird College For Women, Lahore, Pakistan
  • SI NADEEM Department of Zoology, Kinnaird College For Women, Lahore, Pakistan



Guar gum, fibre, Cyamopsis tetragonolobus, fermentation, galactomannan


Guar gum, extracted from the seeds of Cyamopsis tetragonolobus, has gained prominence for its unique properties, forming a thick gel in water and releasing fatty acids through fermentation. Originating in Pakistan and India, it found industrial significance in the US during the 1940s. The galactomannan in guar's endosperm, a polysaccharide of d-mannose and d-galactose, imparts rapid solubility, pH stability, and biodegradability. Beyond its industrial applications, guar gum exhibits a myriad of health benefits. Delving into the botanical symphony of guar seeds reveals a poetic composition, and enzymatic exploration unravels the whimsical ballet of galactose side groups. Guar gum transcends its botanical origins to become a dietary sage, influencing serum cholesterol levels and aiding in weight management. Its journey through the digestive system orchestrates nuanced reductions in blood glucose and insulin, showcasing its potential for diabetes assistance.The manufacturing process involves splitting, hydration, and various treatments, resulting in guar gum's characteristics as a thickening agent with tasteless and odorless properties. Stability studies affirm its consistent performance over time, and its safety for target species, consumers, and the environment is established. Exploring guar gum's therapeutic applications reveals its potential in wound healing, inflammatory bowel disease treatment, and as a preventive measure against ulcers. Its role as a dietary fiber extends to managing irritable bowel syndrome symptoms, reducing blood sugar and cholesterol levels, promoting weight loss, and aiding in regular bowel movements. The article recommends a daily intake of 28g for adult women and 36g for men, achievable through the consumption of guar gum. Clinical studies demonstrate its positive impact on duodenal ulcers, providing relief, increasing satiety, and preventing symptoms. With its multifaceted applications, guar gum emerges as a fascinating substance intertwining chemistry, medicine, and industry.


Todd, P. A., Benfield, P., & Goa, K. L. (1990). Guar gum: a review of its pharmacological properties, and use as a dietary adjunct in hypercholesterolaemia. Drugs, 39, 917-928. DOI:

Nandkishore, T., Usha, J., Sumit, M., & Siddiqui, M. Z. (2016). Guar gum as a promising starting material for diverse applications: a review. International Journal of Biological Macromolecules, 88, 361-372., DOI:

Mudgil, D., Barak, S., & Khatkar, B. S. (2014). Guar gum: processing, properties and food applications—a review. Journal of food science and technology, 51, 409-418. DOI:

Ghosh Auddy, R., Abdullah, M. F., Das, S., Roy, P., Datta, S., & Mukherjee, A. (2013). New guar biopolymer silver nanocomposites for wound healing applications. BioMed research international, 2013. 912458. DOI:

Khan, M. U. A., Raza, M. A., Razak, S. I. A., Abdul Kadir, M. R., Haider, A., Shah, S. A., ... & Aftab, S. (2020). Novel functional antimicrobial and biocompatible arabinoxylan/guar gum hydrogel for skin wound dressing applications. Journal of tissue engineering and regenerative medicine, 14(10), 1488-1501. doi: 10.1002/term.3115. DOI:

Orsu, P., & Matta, S. (2020). Fabrication and characterization of carboxymethyl guar gum nanocomposite for application of wound healing. International Journal of Biological Macromolecules, 164, 2267-2276. doi: 10.1016/j.ijbiomac.2020.07.322. DOI:

Bhubhanil, S., Talodthaisong, C., Khongkow, M., Namdee, K., Wongchitrat, P., Yingmema, W., ... & Kulchat, S. (2021). Enhanced wound healing properties of guar gum/curcumin-stabilized silver nanoparticle hydrogels. Scientific Reports, 11(1), 21836. doi: 10.1038/s41598-021-01262-x. DOI:

Horii, Y., Uchiyama, K., Toyokawa, Y., Hotta, Y., Tanaka, M., Yasukawa, Z., ... & Itoh, Y. (2016). Partially hydrolyzed guar gum enhances colonic epithelial wound healing via activation of RhoA and ERK1/2. Food & function, 7(7), 3176-3183. DOI:

Palem, R. R., Rao, K. M., & Kang, T. J. (2019). Self-healable and dual-functional guar gum-grafted-polyacrylamidoglycolic acid-based hydrogels with nano-silver for wound dressings. Carbohydrate polymers, 223, 115074. doi: 10.1016/j.carbpol.2019.115074. DOI:

Hartemink, R., Schoustra, S. E., & Rombouts, F. M. (1999). Degradation of guar gum by intestinal bacteria. Bioscience and microflora, 18(1), 17-25.. DOI:

Greenberg, N. A., & Sellman, D. (1998). Partially hydrolyzed guar gum as a source of fiber. Cereal Foods World, 43(9), 703-707.

Slavin, J. L., & Greenberg, N. A. (2003). Partially hydrolyzed guar gum: clinical nutrition uses. Nutrition, 19(6), 549-552. doi: 10.1016/s0899-9007(02)01032-8. DOI:

Giannini, E. G., Mansi, C., Dulbecco, P., & Savarino, V. (2006). Role of partially hydrolyzed guar gum in the treatment of irritable bowel syndrome. Nutrition, 22(3), 334-342. DOI:

Dartois A, Singh J, Kaur L, Singh H. Influence of guar gum on the in vitro starch digestibility—rheological and microstructural characteristics. Food Biophysics. 2010;5(3):149-60. doi: 10.1016/j.nut.2005.10.003. DOI:

Butt, M. S., Shahzadi, N., Sharif, M. K., & Nasir, M. (2007). Guar gum: a miracle therapy for hypercholesterolemia, hyperglycemia and obesity. Critical reviews in food science and nutrition, 47(4), 389-396. doi: 10.1080/10408390600846267 DOI:

Rideout, T. C., Harding, S. V., Jones, P. J., & Fan, M. Z. (2008). Guar gum and similar soluble fibers in the regulation of cholesterol metabolism: current understandings and future research priorities. Vascular health and risk management, 4(5), 1023-1033. doi: 10.2147/vhrm.s3512. DOI:

Yoon, S. J., Chu, D. C., & Juneja, L. R. (2008). Chemical and physical properties, safety and application of partially hydrolized guar gum as dietary fiber. Journal of Clinical Biochemistry and Nutrition, 42(1), 1-7. doi: 10.3164/jcbn.2008001. DOI:

Jhundoo, H. D., Siefen, T., Liang, A., Schmidt, C., Lokhnauth, J., Moulari, B., ... & Lamprecht, A. (2021). Anti-inflammatory effects of acacia and guar gum in 5-amino salicylic acid formulations in experimental colitis. International Journal of Pharmaceutics: X, 3, 100080. doi: 10.1016/j.ijpx.2021.100080 DOI:

Gamal-Eldeen, A. M., Amer, H., & Helmy, W. A. (2006). Cancer chemopreventive and anti-inflammatory activities of chemically modified guar gum. Chemico-Biological Interactions, 161(3), 229-240. doi: 10.1016/j.cbi.2006.03.010. DOI:

Anderson, J. W., Baird, P., Davis Jr, R. H., Ferreri, S., Knudtson, M., Koraym, A., ... & Williams, C. L. (2009). Health benefits of dietary fiber. Nutrition reviews, 67(4), 188-205. doi: 10.1111/j.1753-4887.2009.00189.x DOI:

Harju, E., & Mäkelä, J. (1987). Reduction of Postprandial Hyperglycemia by Guar Gum in Symptomatic Patients 5–10 Years following Proximal Selective Vagotomy. Digestive surgery, 4(2), 106-109. DOI:

Harju, E. J., & Larmi, T. K. J. (1985). Effect of guar gum added to the diet of patients with duodenal ulcer. Journal of Parenteral and Enteral Nutrition, 9(4), 496-500. doi: 10.1177/0148607185009004496. DOI:




How to Cite

AWAN, S., FATIMA, Z., KAMRAN, S., KHAN, A., FATIMA, T., IMRAN, S., SHABBIR, M., & NADEEM, S. (2024). GUAR GUM IN THERAPEUTICS: A SUCCINCT EXPLORATION . Bulletin of Biological and Allied Sciences Research, 2024(1), 60.